原著論文 Original Articles

2023年

*equal contribution #corresponding author
 

  1. Emori C, Kodani M, Abbasi F, Mori M, #Ikawa M
    PABPN1L is required for maternal mRNA degradation after meiosis resumption
    J Reprod Dev. 2023 Dec 7. doi: 10.1262/jrd.2023-077. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/38057116/
     
  2. #Ogawa Y, #Lu Y, Kiyozumi D, Chang H, Ikawa M
    CRISPR/Cas9-mediated genome editing reveals seven testis-enriched transmembrane glycoproteins dispensable for male fertility in mice
    Andrology. 2023 Dec 12. doi: 10.1111/andr.13564. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/38084666/
     
  3. #Shimada K, #Ikawa M
    CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility
    Development. 2023 Nov 1;150(21):dev201724. doi: 10.1242/dev.201724. Epub 2023 Oct 30.
    https://pubmed.ncbi.nlm.nih.gov/37882665/
     
  4. #Kiyozumi D, Ikawa M.
    ADGRG2 is dispensable for lumicrine signalling regulating epididymal initial segment differentiation and gene expression.
    Biology of Reproduction.  ioad087. Published online 02 August 2023. doi: 10.1093/biolre/ioad087/7235675
    https://pubmed.ncbi.nlm.nih.gov/37531264/
     
  5. #Shimada K, Lu Y, #Ikawa M.
    Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility.
    Exp Anim.  2023 Jul 10. doi: 10.1538/expanim.23-0055. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/37423748/
     
  6. #Kiyozumi D, Shimada K, Chalick M, Emori C, Kodani M, Oura S, Noda T, Endo T,  Matzuk MM,  #Wreschner DH, #Ikawa M.
    A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility
    Nat Commun. 2023 Apr 24;14(1):2354. doi: 10.1038/s41467-023-37984-x.
    https://pubmed.ncbi.nlm.nih.gov/37095084/
     
  7. Shirai T, Nakai A, Ando E, Fujimoto J, Leach S, Arimori T, Higo D, van Eerden FJ, Tulyeu J, Liu YC, Okuzaki D, Murayama MA, Miyata H, Nunomura K, Lin B, Tani A, Kumanogoh A, Ikawa M, Wing JB, Standley DM, Takagi J, #Suzuki K.
    Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex. 
    Sci Immunol. 2023 Mar 31;8(81):eadc9324. doi: 10.1126/sciimmunol.adc9324. Epub 2023 Mar 31.
    https://pubmed.ncbi.nlm.nih.gov/37000855/
     
  8. Huang X, Miyata H, Wang H, Mori G, Iida-Norita R, Ikawa M, Percudani R, #Chung JJ. 
    A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking.
    bioRxiv [Preprint]. 2023 Mar 17:2023.03.17.532952. doi: 10.1101/2023.03.17.532952.
    https://pubmed.ncbi.nlm.nih.gov/36993167/
     
  9. Miyake T, Inoue Y, Shao X, Seta T, Aoki Y, Nguyen Pham KT, Shichino Y, Sasaki J, Sasaki T, Ikawa M, Yamaguchi Y, Okamura H, Iwasaki S, #Doi M. 
    Minimal upstream open reading frame of Per2 mediates phase fitness of the circadian clock to day/night physiological body temperature rhythm.
    Cell Rep. 2023 Mar 28;42(3):112157. doi: 10.1016/j.celrep.2023.112157. Epub 2023 Mar 6. 
    https://pubmed.ncbi.nlm.nih.gov/36882059/
     
  10. #Shimada K, Park S, Oura S, Noda T, Morohoshi A, #Matzuk MM, #Ikawa M.
    TSKS localizes to nuage in spermatids and regulates cytoplasmic elimination during spermiation.
    Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2221762120. doi: 10.1073/pnas.2221762120. Epub 2023 Mar 7.
    https://pubmed.ncbi.nlm.nih.gov/36881620/
     
  11. Kuribayashi S, #Fukuhara S, Tsujimura G, Imanaka T, Okada K, Ueda N, Takezawa K, Kiuchi H, Saito S, Takahashi Y, Kioka H, Oura S, Shimada K, Ikawa M, Nonomura N.
    Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity.
    Reprod Med Biol. 2023 Feb 23;22(1):e12507. doi: 10.1002/rmb2.12507.
    https://pubmed.ncbi.nlm.nih.gov/36845001/
     
  12. Lu Y, Shimada K, Tang S, Zhang J, Ogawa Y, Noda T, Shibuya H, #Ikawa M.
    1700029I15Rik orchestrates the biosynthesis of acrosomal membrane proteins required for sperm-egg interaction.
    Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2207263120. doi: 10.1073/pnas.2207263120. Epub 2023 Feb 14.
    https://pubmed.ncbi.nlm.nih.gov/36787362/
     
  13. Lu Y, Nagamori I, Kobayashi H, Kojima-Kita K, Shirane K, Chang HY, Nishimura T, Koyano T, Yu Z, Castañeda JM, Matsuyama M, #Kuramochi-Miyagawa S, #Matzuk MM, #Ikawa M.
    ADAD2 functions in spermiogenesis and piRNA biogenesis in mice.
    Andrology. 2023 Jan 25. doi: 10.1111/andr.13400. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/36698249/
     
  14. *Morohoshi A, #*Miyata H, Tokuhiro K, Iida-Norita R, Noda T, Fujihara Y, #Ikawa M.
    Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.
    Sci Adv. 2023 Jan 25;9(4):eade7607. doi: 10.1126/sciadv.ade7607. Epub 2023 Jan 25.
    https://pubmed.ncbi.nlm.nih.gov/36696506/
     
  15. Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, Hashimoto R, Shigesada N, Takahashi J, Tachibana M, Tanaka S, Obana M, Hino N, Ikawa M, Tsujikawa K, Ono C, Matsuura Y, Kidoya H, Takakura N, Kubota Y, Doi T, Takayama K, Yoshioka Y, Fujio Y, #Okada Y.
    Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models.
    Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2213317120. doi: 10.1073/pnas.2213317120. Epub 2023 Jan 12.
    https://pubmed.ncbi.nlm.nih.gov/36634143/
     
  16. Kaneda Y, #Miyata H, Shimada K, Oura S, #Ikawa M.
    Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice.
    Andrology. 2023 Jan 4. doi: 10.1111/andr.13378. Online ahead of print.
    https://pubmed.ncbi.nlm.nih.gov/36598146/